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Novartis unveils breakthroughs in iron catalysis and p38α inhibitors

3 statements, Aug 28, 2026 00:04 UTC to Sep 23, 2026 21:35 UTC
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Statements (3)

  1. Bullish

    Novartis reported a breakthrough in the discovery of potent and selective MAO-B inhibitors from a morpholine-substituted chalcone library, with TC12 identified as the strongest inhibitor.

    pubmed.ncbi.nlm.nih.gov
  2. Bullish

    Novartis reported a first-in-class p38α-isoform selective inhibitor with 12,000-fold selectivity improvement over currently available compounds.

    pubmed.ncbi.nlm.nih.gov
  3. Bullish

    Novartis reported a breakthrough in nonheme iron catalysis for indole oxidation, enabling efficient synthesis of natural products and pharmaceuticals.

    pubmed.ncbi.nlm.nih.gov